Gold complex compounds that inhibit drug-resistant Staphylococcus aureus by targeting thioredoxin reductase
IntroductionThere is a significant need for new antimicrobial compounds that are effective against drug-resistant microbes. Thioredoxin reductase (TrxR) is critical in redox homeostasis and was identified as a potential drug target and confirmed through inhibition by compounds auranofin and Bay11-70...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Antibiotics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frabi.2023.1179354/full |