Crosstalk between p53 modifiers at PML bodies

Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage. Regulation of p53 activity by post-translational modifications has been linked to promyelocytic leukemia nuclear bodies (PML-NBs), w...

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Bibliographic Details
Main Authors: Sonja Matt, Thomas G Hofmann
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2015.1074335