Crosstalk between p53 modifiers at PML bodies
Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage. Regulation of p53 activity by post-translational modifications has been linked to promyelocytic leukemia nuclear bodies (PML-NBs), w...
Main Authors: | Sonja Matt, Thomas G Hofmann |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-05-01
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Series: | Molecular & Cellular Oncology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/23723556.2015.1074335 |
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