Isolation and molecular characterization of a major hemolymph serpin from the triatomine, Panstrongylus megistus

Isolation and molecular characterization of a major hemolymph serpin from the triatomine, Panstrongylus megistus

Abstract Background Chagas disease kills 2.5 thousand people per year of 15 million persons infected in Latin America. The disease is caused by the protozoan, Trypanosome cruzi, and vectored by triatomine insects, including Panstrongylus megistus, an important vector in Brazil. Medicines treating Ch...

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Bibliographic Details
Main Authors: Carlos JC Moreira, Peter J Waniek, Richard H Valente, Paulo C Carvalho, Jonas Perales, Denise Feder, Reinaldo B Geraldo, Helena C Castro, Patricia Azambuja, Norman A Ratcliffe, Cícero B Mello
Format: Article
Language:English
Published: BMC 2014-01-01
Series:Parasites & Vectors
Subjects:
Panstrongylus megistus
Serpin
Hemolymph
Serine protease
Cleavage sites
T. cruzi serpin modulation
Online Access:https://doi.org/10.1186/1756-3305-7-23

Internet

https://doi.org/10.1186/1756-3305-7-23

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