A New Method of Myostatin Inhibition in Mice via Oral Administration of <i>Lactobacillus casei</i> Expressing Modified Myostatin Protein, BLS-M22

A New Method of Myostatin Inhibition in Mice via Oral Administration of <i>Lactobacillus casei</i> Expressing Modified Myostatin Protein, BLS-M22

Myostatin is a member of the transforming growth factor-beta superfamily and is an endogenous negative regulator of muscle growth. This study aimed to determine whether an oral administration of <i>Lactobacillus casei</i> expressing modified human myostatin (BLS-M22) could elicit suffici...

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Bibliographic Details
Main Authors: Dong Kyung Sung, Hyeongseop Kim, Sang Eon Park, Jiwon Lee, Ju-A Kim, Young-Chul Park, Hong Bae Jeon, Jong Wook Chang, Jeehun Lee
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
myostatin
<i>Lactobacillus casei</i>
poly-gamma-glutamic acid synthetase A
Duchenne muscular dystrophy
<i>mdx</i> mouse
Online Access:https://www.mdpi.com/1422-0067/23/16/9059

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https://www.mdpi.com/1422-0067/23/16/9059

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