In silico analysis reveals the co-existence of CRISPR-Cas type I-F1 and type I-F2 systems and its association with restricted phage invasion in Acinetobacter baumannii

In silico analysis reveals the co-existence of CRISPR-Cas type I-F1 and type I-F2 systems and its association with restricted phage invasion in Acinetobacter baumannii

IntroductionAcinetobacter baumannii, an opportunistic pathogen, rapidly acquires antibiotic resistance, thus compelling researchers to develop alternative treatments at utmost priority. Phage-based therapies are of appreciable benefit; however, CRISPR-Cas systems are a major constraint in this appro...

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Bibliographic Details
Main Authors: Gulshan Yadav, Ruchi Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
Acinetobacter baumannii
CRISPR-Cas
co-existence
type I-F1
type I-F2
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.909886/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.909886/full

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