Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration but suppress invasiveness, migration, and proliferation of melanoma cells

Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration but suppress invasiveness, migration, and proliferation of melanoma cells

Melanoma is the deadliest form of skin cancer and develops from the melanocytes that are responsible for the pigmentation of the skin. The skin is also a highly regenerative organ, harboring a pool of undifferentiated melanocyte stem cells that proliferate and differentiate into mature melanocytes d...

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Bibliographic Details
Main Authors: Esra Katkat, Yeliz Demirci, Guillaume Heger, Doga Karagulle, Irene Papatheodorou, Alvis Brazma, Gunes Ozhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
wound healing
melanoma
proliferation
differentiation
migration
epithelial-to-mesenchymal transition
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1297910/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1297910/full

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