Bone Growth Induction in Mucopolysaccharidosis IVA Mouse

Bone Growth Induction in Mucopolysaccharidosis IVA Mouse

Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is caused by a deficiency of the N-acetylgalactosamine-6-sulfate-sulfatase (GALNS) enzyme, leading to the accumulation of glycosaminoglycans (GAG), keratan sulfate (KS) and chondroitin-6-sulfate (C6S), mainly in cartilage and bone. This lysosom...

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Bibliographic Details
Main Authors: Estera Rintz, Angélica María Herreño-Pachón, Betul Celik, Fnu Nidhi, Shaukat Khan, Eliana Benincore-Flórez, Shunji Tomatsu
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
C-type natriuretic peptide
Morquio A syndrome
ossification
AAV gene therapy
Online Access:https://www.mdpi.com/1422-0067/24/12/9890

Internet

https://www.mdpi.com/1422-0067/24/12/9890

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