Epigenetic regulation of MIR145 core promoter controls miR-143/145 cluster in bladder cancer progression and treatment outcome

Epigenetic regulation of MIR145 core promoter controls miR-143/145 cluster in bladder cancer progression and treatment outcome

Owing to its highly heterogeneous molecular landscape, bladder cancer (BlCa) is still characterized by non-personalized treatment and lifelong surveillance. Motivated by our previous findings on miR-143/145 value in disease prognosis, we have studied the underlying epigenetic regulation of the miR-1...

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Bibliographic Details
Main Authors: Katerina-Marina Pilala, Maria-Alexandra Papadimitriou, Konstantina Panoutsopoulou, Petros Barbarigos, Panagiotis Levis, Georgios Kotronopoulos, Konstantinos Stravodimos, Andreas Scorilas, Margaritis Avgeris
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs
DNA methylation
epigenetics
prognosis
tumor progression
miRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253122002670

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http://www.sciencedirect.com/science/article/pii/S2162253122002670

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