Innovative Computerized Dystrophin Quantification Method Based on Spectral Confocal Microscopy

Innovative Computerized Dystrophin Quantification Method Based on Spectral Confocal Microscopy

Several clinical trials are working on drug development for Duchenne and Becker muscular dystrophy (DMD and BMD) treatment, and, since the expected increase in dystrophin is relatively subtle, high-sensitivity quantification methods are necessary. There is also a need to quantify dystrophin to reach...

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Bibliographic Details
Main Authors: Anna Codina, Mònica Roldán, Daniel Natera-de Benito, Carlos Ortez, Robert Planas, Leslie Matalonga, Daniel Cuadras, Laura Carrera, Jesica Exposito, Jesus Marquez, Cecilia Jimenez-Mallebrera, Josep M. Porta, Andres Nascimento, Cristina Jou
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
dystrophin
Duchenne muscular dystrophy
Becker muscular dystrophy
confocal microscopy
fluorescence quantification
spectral imaging
Online Access:https://www.mdpi.com/1422-0067/24/7/6358

Internet

https://www.mdpi.com/1422-0067/24/7/6358

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