UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway

UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway

Human hepatocellular carcinoma (HCC) has a high mortality rate because of the dearth of effective treatments. Multiple studies have shown that overexpression of UPF1, a key nonsense-mediated mRNA decay (NMD) factor, reduces HCC growth through various cell signaling pathways. However, the mechanism b...

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Bibliographic Details
Main Authors: Suman Lee, Yukyung Hwang, Tae Hun Kim, Jaemin Jeong, Dongho Choi, Jungwook Hwang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
UPF1
hepatocellular carcinoma
posttranscriptional regulation
DUSP1
Online Access:https://www.mdpi.com/2227-9059/10/4/793

Internet

https://www.mdpi.com/2227-9059/10/4/793

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