Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms
Therapy-related myeloid neoplasms (t-MN) are a growing concern due to the continued use of cytotoxic therapies to treat malignancies. Cytotoxic therapies have been shown to drive therapy-induced senescence in normal tissues, including in the bone marrow microenvironment (BMME), which plays a crucial...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-08-01
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Series: | Journal of Bone Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137424001003 |