A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors.

A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors.

BACKGROUND: Many neglected tropical infectious diseases affecting humans are transmitted by arthropods such as mosquitoes and ticks. New mode-of-action chemistries are urgently sought to enhance vector management practices in countries where arthropod-borne diseases are endemic, especially where vec...

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Bibliographic Details
Main Authors: Jason M Meyer, Karin F K Ejendal, Larisa V Avramova, Elisabeth E Garland-Kuntz, Gloria I Giraldo-Calderón, Tarsis F Brust, Val J Watts, Catherine A Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3265452?pdf=render

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http://europepmc.org/articles/PMC3265452?pdf=render

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