Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape
The provision of costimulatory signals to T cells are known to be vital in the direction and induction of a T cell driven response. Here the authors show an optimal T cell response requires a costimulatory induced modification of the transcript landscape and achieves this via modulation of the RNA b...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31228-0 |