Recent advances in melittin-based nanoparticles for antitumor treatment: from mechanisms to targeted delivery strategies

Abstract As a naturally occurring cytolytic peptide, melittin (MLT) not only exhibits a potent direct tumor cell-killing effect but also possesses various immunomodulatory functions. MLT shows minimal chances for developing resistance and has been recognized as a promising broad-spectrum antitumor d...

Full description

Bibliographic Details
Main Authors: Xiang Yu, Siyu Jia, Shi Yu, Yaohui Chen, Chengwei Zhang, Haidan Chen, Yanfeng Dai
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-023-02223-4