Phenotypic variance explained by local ancestry in admixed African Americans

Phenotypic variance explained by local ancestry in admixed African Americans

We surveyed 26 quantitative traits and disease outcomes to understand the proportion of phenotypic variance explained by local ancestry in admixed African Americans. After inferring local ancestry as the number of African-ancestry chromosomes at hundreds of thousands of genotyped loci across all aut...

Full description

Bibliographic Details
Main Authors: Daniel eShriner, Amy R. Bentley, Ayo Priscille Doumatey, Guanjie eChen, Jie eZhou, Adebowale eAdeyemo, Charles N. Rotimi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Genetics
Subjects:
Health Disparities
complex traits
ancestry
random effects
phenotypic variance explained
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00324/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00324/full

Similar Items