HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT3

HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT3

Fungal infections cause serious health problems, especially in patients with an immune-deficiency. Histone deacetylase 11 (HDAC11) mediates various immune functions, yet little is known about its role in regulating host immune responses to fungal infection. Here we report that HDAC11 negatively cont...

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Bibliographic Details
Main Authors: Han Wu, Xiaofan Yin, Xibao Zhao, Zherui Wu, Yue Xiao, Qianqian Di, Ping Sun, Haimei Tang, Jiazheng Quan, Weilin Chen
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
Histone deacetylase 11
Fungal infection
Candida albicans
Nos2
STAT3
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002336

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http://www.sciencedirect.com/science/article/pii/S2213231722002336

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