Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects

Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects

Injectable bone biomaterials like bone cement should be designed and fabricated with certain biological criteria, which include: 1) recruitment and polarization of the macrophages from M1 (pro-inflammatory) to M2 (anti-inflammatory) phenotype, 2) enhance vascularization, and 3) activate osteogenic d...

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Bibliographic Details
Main Authors: Shuaijie Li, Liyan Zhang, Chunyu Liu, Jua Kim, Kun Su, Tingli Chen, Limin Zhao, Xiaomei Lu, Hao Zhang, Yinglin Cui, Xu Cui, Feng Yuan, Haobo Pan
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-05-01
Series:Bioactive Materials
Subjects:
Borosilicate glass bone cement
Immunomodulation
Angiogenesis
Osteogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22004455

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http://www.sciencedirect.com/science/article/pii/S2452199X22004455

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