Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling

Poly-ADP-ribose polymerases (PARPs) are enzymes that catalyze ADP-ribosylation and play critical roles in normal and disease settings. The PARP family member, PARP7, is a mono-ADP-ribosyltransferase that has been suggested to play a tumor suppressive role in breast, ovarian, and colorectal cancer. H...

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Bibliographic Details
Main Authors: Teddy Kamata, Chun-Song Yang, Tiffany A. Melhuish, Henry F. Frierson Jr., David Wotton, Bryce M. Paschal
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/363