Intermediate Filaments as Effectors of Cancer Development and Metastasis: A Focus on Keratins, Vimentin, and Nestin

Intermediate filament (IF) proteins make up the largest family of cytoskeletal proteins in metazoans, and are traditionally known for their roles in fostering structural integrity in cells and tissues. Remarkably, individual IF genes are tightly regulated in a fashion that reflects the type of tissu...

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Bibliographic Details
Main Authors: Pooja Sharma, Sarah Alsharif, Arwa Fallatah, Byung Min Chung
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/5/497