Proteomic and Phenotypic Studies of Mycoplasma pneumoniae Revealed Macrolide-Resistant Mutation (A2063G) Associated Changes in Protein Composition and Pathogenicity of Type I Strains

Proteomic and Phenotypic Studies of Mycoplasma pneumoniae Revealed Macrolide-Resistant Mutation (A2063G) Associated Changes in Protein Composition and Pathogenicity of Type I Strains

ABSTRACT Mycoplasma pneumoniae (MP) is an important respiratory pathogen, the prevalence of macrolide-resistant MP (mainly containing A2063G mutation in 23S rRNA) increased in recent years. Epidemiological studies suggest a higher prevalence of type I resistant (IR) strains than corresponding sensit...

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Bibliographic Details
Main Authors: Zhikun Zhang, Haiwei Dou, Qing Yuan, Dawei Shi, Ruijie Wan, Peng Tu, Deli Xin, Shuilong Guo
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Mycoplasma pneumoniae
proteomics
A2063G
proliferation
adhesion
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04613-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04613-22

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