High FAAP24 expression reveals poor prognosis and an immunosuppressive microenvironment shaping in AML

High FAAP24 expression reveals poor prognosis and an immunosuppressive microenvironment shaping in AML

Abstract Background As a core member of the FA complex, in the Fanconi anemia pathway, FAAP24 plays an important role in DNA damage repair. However, the association between FAAP24 and patient prognosis in AML and immune infiltration remains unclear. The purpose of this study was to explore its expre...

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Bibliographic Details
Main Authors: Xiebing Bao, Jingyun Chi, Yiwei Zhu, Minfeng Yang, Jiahui Du, Zaixiang Tang, Xiaogang Xu, Genxiang Mao, Zhibing Wu, Jun Chen, Jingsheng Hua, Ting Xu, Song-Bai Liu
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cancer Cell International
Subjects:
FAAP24
AML
Prognosis
Immunosuppression
Chelerythrine
Online Access:https://doi.org/10.1186/s12935-023-02937-3

Internet

https://doi.org/10.1186/s12935-023-02937-3

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