Taming active transposons at Drosophila telomeres: The interconnection between HipHop's roles in capping and transcriptional silencing.

Drosophila chromosomes are elongated by retrotransposon attachment, a process poorly understood. Here we characterized a mutation affecting the HipHop telomere-capping protein. In mutant ovaries and the embryos that they produce, telomere retrotransposons are activated and transposon RNP accumulates...

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Bibliographic Details
Main Authors: Min Cui, Yaofu Bai, Kaili Li, Yikang S Rong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009925