Engineering homologous platelet-rich plasma, platelet-rich plasma-derived exosomes, and mesenchymal stem cell-derived exosomes-based dual-crosslinked hydrogels as bioactive diabetic wound dressings

Engineering homologous platelet-rich plasma, platelet-rich plasma-derived exosomes, and mesenchymal stem cell-derived exosomes-based dual-crosslinked hydrogels as bioactive diabetic wound dressings

The management of diabetic wounds remains a critical therapeutic challenge. Platelet-rich plasma (PRP) gel, PRP-derived exosomes (PRP-Exos), and mesenchymal stem cell-derived exosomes (MSC-Exos) have demonstrated therapeutic potential in wound treatment. Unfortunately, their poor mechanical properti...

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Bibliographic Details
Main Authors: Bianza Moise Bakadia, Abeer Ahmed Qaed Ahmed, Lallepak Lamboni, Zhijun Shi, Biampata Mutu Mukole, Ruizhu Zheng, Mazono Pierre Mbang, Bi Zhang, Mario Gauthier, Guang Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-10-01
Series:Bioactive Materials
Subjects:
Platelet-rich plasma (PRP)
Exosomes (Exos)
Silk protein
Dual-crosslinked hydrogel
Diabetic wound
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23001469

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http://www.sciencedirect.com/science/article/pii/S2452199X23001469

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