Improvement of multilineage hematopoiesis in hematopoietic stem cell-transferred c-kit mutant NOG-EXL humanized mice

Improvement of multilineage hematopoiesis in hematopoietic stem cell-transferred c-kit mutant NOG-EXL humanized mice

Abstract Human hematopoietic stem cell (HSC)-transferred humanized mice are valuable models for exploring human hematology and immunology. However, sufficient recapitulation of human hematopoiesis in mice requires large quantities of enriched human CD34+ HSCs and total-body irradiation for adequate...

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書目詳細資料
Main Authors: Ryoji Ito, Yusuke Ohno, Yunmei Mu, Yuyo Ka, Shuko Ito, Maiko Emi-Sugie, Misa Mochizuki, Kenji Kawai, Motohito Goto, Tomoyuki Ogura, Riichi Takahashi, Akira Niwa, Tatsutoshi Nakahata, Mamoru Ito
格式: Article
語言:English
出版: BMC 2024-06-01
叢編:Stem Cell Research & Therapy
主題:
Hematopoietic stem cells
Hematopoiesis
Humanized mice
NOG
CD34+ cells
在線閱讀:https://doi.org/10.1186/s13287-024-03799-w

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https://doi.org/10.1186/s13287-024-03799-w

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