Memory CD8 T Cells Generated by Cytomegalovirus Vaccine Vector Expressing NKG2D Ligand Have Effector-Like Phenotype and Distinct Functional Features

Memory CD8 T Cells Generated by Cytomegalovirus Vaccine Vector Expressing NKG2D Ligand Have Effector-Like Phenotype and Distinct Functional Features

Viral vectors have emerged as a promising alternative to classical vaccines due to their great potential for induction of a potent cellular and humoral immunity. Cytomegalovirus (CMV) is an attractive vaccine vector due to its large genome with many non-essential immunoregulatory genes that can be e...

Full description

Bibliographic Details
Main Authors: Marko Šustić, Maja Cokarić Brdovčak, Berislav Lisnić, Jelena Materljan, Vanda Juranić Lisnić, Carmen Rožmanić, Daniela Indenbirken, Lea Hiršl, Dirk H. Busch, Ilija Brizić, Astrid Krmpotić, Stipan Jonjić
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
memory T cells
CD8 T lymphocytes
cytomegalovirus
vaccine vector
tumor vaccine
Klrg1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.681380/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.681380/full

Similar Items