Differences in Growth Properties among Two Human Cytomegalovirus Glycoprotein O Genotypes

Differences in Growth Properties among Two Human Cytomegalovirus Glycoprotein O Genotypes

Glycoprotein O (gO) of the human cytomegalovirus (HCMV) is the critical subunit of the envelope trimer gH/gL/gO as it interacts with platelet-derived growth factor alpha receptor upon fibroblast entry, and triggers gB-mediated fusion for fibroblast and epithelial cell infection. Eight genotypes (GT)...

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Bibliographic Details
Main Authors: Julia Kalser, Barbara Adler, Michael Mach, Barbara Kropff, Elisabeth Puchhammer-Stöckl, Irene Görzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
HCMV
glycoprotein O
trimeric complex
tropism
epithelial cells
fibroblasts
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01609/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01609/full

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