Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies

Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies

The absence of anti-cytomegalovirus (CMV) immunoglobulin G (IgG) is used to classify pretransplant patients as naïve for CMV infection (CMVneg patients). This study assessed whether pretransplant CMV-specific T-cell immunity exists in CMVneg patients and whether it protects against CMV infection aft...

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Bibliographic Details
Main Authors: Nicolle H. R. Litjens, Ling Huang, Burç Dedeoglu, Ruud W. J. Meijers, Jaap Kwekkeboom, Michiel G. H. Betjes
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
cytomegalovirus
T cells
B cells
cellular immunity
humoral immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01137/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01137/full

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