Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF

Through force spectroscopy studies on living bacteria, Viljoen et al. characterise the binding of S. aureus to host von Willebrand factor (vWF). They propose that S. aureus vWF-binding protein triggers an ultra-strong interaction between the adhesin clumping factor A and vWF.

Bibliographic Details
Main Authors: Albertus Viljoen, Felipe Viela, Marion Mathelié-Guinlet, Dominique Missiakas, Giampiero Pietrocola, Pietro Speziale, Yves F. Dufrêne
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01986-6