Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF
Through force spectroscopy studies on living bacteria, Viljoen et al. characterise the binding of S. aureus to host von Willebrand factor (vWF). They propose that S. aureus vWF-binding protein triggers an ultra-strong interaction between the adhesin clumping factor A and vWF.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-01986-6 |
| _version_ | 1828958792300101632 |
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| author | Albertus Viljoen Felipe Viela Marion Mathelié-Guinlet Dominique Missiakas Giampiero Pietrocola Pietro Speziale Yves F. Dufrêne |
| author_facet | Albertus Viljoen Felipe Viela Marion Mathelié-Guinlet Dominique Missiakas Giampiero Pietrocola Pietro Speziale Yves F. Dufrêne |
| author_sort | Albertus Viljoen |
| collection | DOAJ |
| description | Through force spectroscopy studies on living bacteria, Viljoen et al. characterise the binding of S. aureus to host von Willebrand factor (vWF). They propose that S. aureus vWF-binding protein triggers an ultra-strong interaction between the adhesin clumping factor A and vWF. |
| first_indexed | 2024-12-14T08:55:38Z |
| format | Article |
| id | doaj.art-5fb6b6ad101d42848719d50da0b6a208 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-14T08:55:38Z |
| publishDate | 2021-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-5fb6b6ad101d42848719d50da0b6a2082022-12-21T23:08:57ZengNature PortfolioCommunications Biology2399-36422021-04-014111010.1038/s42003-021-01986-6Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWFAlbertus Viljoen0Felipe Viela1Marion Mathelié-Guinlet2Dominique Missiakas3Giampiero Pietrocola4Pietro Speziale5Yves F. Dufrêne6Louvain Institute of Biomolecular Science and Technology, UCLouvainLouvain Institute of Biomolecular Science and Technology, UCLouvainLouvain Institute of Biomolecular Science and Technology, UCLouvainDepartment of Microbiology, The University of ChicagoDepartment of Molecular Medicine, Unit of Biochemistry, University of PaviaDepartment of Molecular Medicine, Unit of Biochemistry, University of PaviaLouvain Institute of Biomolecular Science and Technology, UCLouvainThrough force spectroscopy studies on living bacteria, Viljoen et al. characterise the binding of S. aureus to host von Willebrand factor (vWF). They propose that S. aureus vWF-binding protein triggers an ultra-strong interaction between the adhesin clumping factor A and vWF.https://doi.org/10.1038/s42003-021-01986-6 |
| spellingShingle | Albertus Viljoen Felipe Viela Marion Mathelié-Guinlet Dominique Missiakas Giampiero Pietrocola Pietro Speziale Yves F. Dufrêne Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF Communications Biology |
| title | Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF |
| title_full | Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF |
| title_fullStr | Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF |
| title_full_unstemmed | Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF |
| title_short | Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF |
| title_sort | staphylococcus aureus vwf binding protein triggers a strong interaction between clumping factor a and host vwf |
| url | https://doi.org/10.1038/s42003-021-01986-6 |
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