Essentiality of Succinate Dehydrogenase in <named-content content-type="genus-species">Mycobacterium smegmatis</named-content> and Its Role in the Generation of the Membrane Potential Under Hypoxia

ABSTRACT Succinate:quinone oxidoreductase (Sdh) is a membrane-bound complex that couples the oxidation of succinate to fumarate in the cytoplasm to the reduction of quinone to quinol in the membrane. Mycobacterial species harbor genes for two putative sdh operons, but the individual roles of these t...

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Bibliographic Details
Main Authors: Ildiko Pecsi, Kiel Hards, Nandula Ekanayaka, Michael Berney, Travis Hartman, William R. Jacobs, Gregory M. Cook
Format: Article
Language:English
Published: American Society for Microbiology 2014-08-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01093-14