Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux[S]

Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux[S]

Studies in lipoprotein kinetics almost exclusively rely on steady-state approaches to modeling. Herein, we have used a non-steady-state experimental design to examine the role of cholesteryl ester transfer protein (CETP) in mediating HDL-TG flux in vivo in rhesus macaques, and therefore, we develope...

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Bibliographic Details
Main Authors: David G. McLaren, Stephen F. Previs, Robert D. Phair, Steven J. Stout, Dan Xie, Ying Chen, Gino M. Salituro, Suoyu S. Xu, Jose M. Castro-Perez, Gregory J. Opiteck, Karen O. Akinsanya, Michele A. Cleary, Hayes M. Dansky, Douglas G. Johns, Thomas P. Roddy
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Lipid Research
Subjects:
cholesteryl ester transfer protein
rhesus macaques
lipoproteins
postprandial
non-steady-state dynamics
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Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354390

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http://www.sciencedirect.com/science/article/pii/S0022227520354390

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