Dysfunctional Postnatal Mitochondrial Energy Metabolism in a Patient with Neurodevelopmental Defects Caused by Intrauterine Growth Restriction Due to Idiopathic Placental Insufficiency

Dysfunctional Postnatal Mitochondrial Energy Metabolism in a Patient with Neurodevelopmental Defects Caused by Intrauterine Growth Restriction Due to Idiopathic Placental Insufficiency

We report the case of a four-year-old male patient with a complex medical history born prematurely as the result of intrauterine growth restriction due to placental insufficiency. His clinical manifestations included severe neurodevelopmental deficits, global developmental delay, Pierre-Robin sequen...

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Bibliographic Details
Main Authors: Martine Uittenbogaard, Andrea L. Gropman, Matthew T. Whitehead, Christine A. Brantner, Eliana Gropman, Anne Chiaramello
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
placental insufficiency
fetal growth restriction
neurodevelopmental deficits
OXPHOS deficit
metabolic reprogramming
mitochondrial dysfunction
Online Access:https://www.mdpi.com/1422-0067/25/3/1386

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https://www.mdpi.com/1422-0067/25/3/1386

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