Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis through restoration of Sirt3 expression

AbstractContext Fibroblast senescence was reported to contribute to the pathological development of idiopathic pulmonary fibrosis (IPF), and baicalein is reported to attenuate IPF.Objective This study explores whether baicalein attenuates lung fibrosis by regulating lung fibroblast senescence.Materi...

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Bibliographic Details
Main Authors: Yuan Ji-hong, Ma Yu, Yuan Ling-hong, Gong Jing-jing, Xu Ling-li, Wang Lv, Jin Yong-mei
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Pharmaceutical Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2160767