New Hippolide Derivatives with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Marine Sponge Hippospongia lachne

Five new sesterterpenoids, compounds 1–5, have been isolated from the sponge Hippospongia lachne off Yongxing Island in the South China Sea. The structures of compounds 1–5 were elucidated through extensive spectroscopic analysis, including HRMS, 1D, and 2D NMR experiments. The stereochemistry, in...

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Bibliographic Details
Main Authors: Shu-Juan Piao, Wei-Hua Jiao, Fan Yang, Yang-Hua Yi, Ying-Tong Di, Bing-Nan Han, Hou-Wen Lin
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/7/4096