A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7

A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7

Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction partners....

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Bibliographic Details
Main Authors: Svenja Bockelmann, JohnG.M. Mina, Sergei Korneev, Dina G. Hassan, Dagmar Müller, Angelika Hilderink, Hedwich C. Vlieg, Reinout Raijmakers, AlbertJ.R. Heck, Per Haberkant, JoostC.M. Holthuis
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Lipid Research
Subjects:
click chemistry
lipid transfer protein
mitochondria
phosphatidylcholine
photoaffinity labeling
ceramide transfer protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331394

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http://www.sciencedirect.com/science/article/pii/S0022227520331394

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