Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast.

Correct bioriented attachment of sister chromatids to the mitotic spindle is essential for chromosome segregation. In budding yeast, the conserved protein shugoshin (Sgo1) contributes to biorientation by recruiting the protein phosphatase PP2A-Rts1 and the condensin complex to centromeres. Using pep...

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Bibliographic Details
Main Authors: Galal Yahya, Yehui Wu, Karolina Peplowska, Jennifer Röhrl, Young-Min Soh, Frank Bürmann, Stephan Gruber, Zuzana Storchova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008569