Does different information disclosure on placebo control affect blinding and trial outcomes? A case study of participant information leaflets of randomized placebo-controlled trials of acupuncture

Does different information disclosure on placebo control affect blinding and trial outcomes? A case study of participant information leaflets of randomized placebo-controlled trials of acupuncture

Abstract Background While full disclosure of information on placebo control in participant information leaflets (PILs) in a clinical trial is ethically required during informed consent, there have been concerning voices such complete disclosures may increase unnecessary nocebo responses, breach doub...

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Bibliographic Details
Main Authors: Soyeon Cheon, Hi-Joon Park, Younbyoung Chae, Hyangsook Lee
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Medical Research Methodology
Subjects:
Placebo
Participant information leaflet
Informed consent
Information disclosure
Randomized controlled trial
Blinding
Online Access:http://link.springer.com/article/10.1186/s12874-018-0474-1

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http://link.springer.com/article/10.1186/s12874-018-0474-1

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