MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection

MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection

Abstract Background Cryptosporidium is second only to rotavirus as a cause of moderate-to-severe diarrhea in young children. There are currently no fully effective drug treatments or vaccines for cryptosporidiosis. MicroRNAs (miRNAs) are involved in regulating the innate immune response to Cryptospo...

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Bibliographic Details
Main Authors: Juanfeng Li, Lulu Sun, Fujie Xie, Tianren Shao, Shanbo Wu, Xiaoying Li, Longxian Zhang, Rongjun Wang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Parasites & Vectors
Subjects:
Cryptosporidium parvum
miR-3976
BCL2A1
Apoptosis
Parasite burden
Online Access:https://doi.org/10.1186/s13071-023-05826-w

Internet

https://doi.org/10.1186/s13071-023-05826-w

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