Modeling Myotonic Dystrophy Type 2 Using <i>Drosophila melanogaster</i>

Myotonic dystrophy 2 (DM2) is a genetic multi-systemic disease primarily affecting skeletal muscle. It is caused by CCTGn expansion in intron 1 of the <i>CNBP</i> gene, which encodes a zinc finger protein. DM2 disease has been successfully modeled in <i>Drosophila melanogaster,<...

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Bibliographic Details
Main Authors: Marta Marzullo, Sonia Coni, Assia De Simone, Gianluca Canettieri, Laura Ciapponi
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/18/14182