Enhanced potent immunosuppression of intracellular adipose tissue-derived stem cell extract by priming with three-dimensional spheroid formation

Enhanced potent immunosuppression of intracellular adipose tissue-derived stem cell extract by priming with three-dimensional spheroid formation

Abstract Immunomodulatory properties of mesenchymal stem cells are widely studied, supporting the use of MSCs as cell-based therapy in immunological diseases. This study aims to generate cell-free MSC extract and improves their immunomodulatory potential. Intracellular extracts were prepared from ad...

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Bibliographic Details
Main Authors: Witchayapon Kamprom, Rattanawan Tangporncharoen, Nuttapoom Vongthaiwan, Patcharapa Tragoonlugkana, Jitrada Phetfong, Chatchai Pruksapong, Aungkura Supokawej
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Adipose tissue-derived stem cell
Spheroid
Intracellular extract
Immunomodulation
Cell-free product
Online Access:https://doi.org/10.1038/s41598-024-59910-x

Internet

https://doi.org/10.1038/s41598-024-59910-x

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