Reviving lost binding sites: Exploring calcium‐binding site transitions between human and murine CD23

Reviving lost binding sites: Exploring calcium‐binding site transitions between human and murine CD23

Immunoglobulin E (IgE) is a central regulatory and triggering molecule of allergic immune responses. IgE’s interaction with CD23 modulates both IgE production and functional activities.CD23 is a noncanonical immunoglobulin receptor, unrelated to receptors of other antibody isotypes. Human CD23 is a...

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Bibliographic Details
Main Authors: Veronica F. Ilkow, Anna M. Davies, Balvinder Dhaliwal, Andrew J. Beavil, Brian J. Sutton, James M. McDonnell
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:FEBS Open Bio
Subjects:
calcium
CD23
CTLD
FcεRII
IgE
immunoglobulin E
Online Access:https://doi.org/10.1002/2211-5463.13214

Internet

https://doi.org/10.1002/2211-5463.13214

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