High IGKC-Expressing Intratumoral Plasma Cells Predict Response to Immune Checkpoint Blockade

High IGKC-Expressing Intratumoral Plasma Cells Predict Response to Immune Checkpoint Blockade

Resistance to Immune Checkpoint Blockade (ICB) constitutes the current limiting factor for the optimal implementation of this novel therapy, which otherwise demonstrates durable responses with acceptable toxicity scores. This limitation is exacerbated by a lack of robust biomarkers. In this study, w...

Full description

Bibliographic Details
Main Authors: Juan Luis Onieva, Qingyang Xiao, Miguel-Ángel Berciano-Guerrero, Aurora Laborda-Illanes, Carlos de Andrea, Patricia Chaves, Pilar Piñeiro, Alicia Garrido-Aranda, Elena Gallego, Belén Sojo, Laura Gálvez, Rosario Chica-Parrado, Daniel Prieto, Elisabeth Pérez-Ruiz, Angela Farngren, María José Lozano, Martina Álvarez, Pedro Jiménez, Alfonso Sánchez-Muñoz, Javier Oliver, Manuel Cobo, Emilio Alba, Isabel Barragán
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
immunotherapy
biomarkers
melanoma
Online Access:https://www.mdpi.com/1422-0067/23/16/9124

Internet

https://www.mdpi.com/1422-0067/23/16/9124

Similar Items