<i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> Candidate Vaccine Strains Are Pro-apoptotic in RAW 264.7 Murine Macrophages

<i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> Candidate Vaccine Strains Are Pro-apoptotic in RAW 264.7 Murine Macrophages

<i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> (MAP) is the etiological agent of Johne’s disease, a severe gastroenteritis of ruminants. This study developed a model cell culture system to rapidly screen MAP mutants with vaccine potential for apoptosis. Two wild-ty...

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Bibliographic Details
Main Authors: Raul G. Barletta, John P. Bannantine, Judith R. Stabel, Ezhumalai Muthukrishnan, Dirk K. Anderson, Enakshy Dutta, Vamsi Manthena, Mostafa Hanafy, Denise K. Zinniel
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Vaccines
Subjects:
<i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>
macrophages
virulence
apoptosis
necrosis
vaccine
Online Access:https://www.mdpi.com/2076-393X/11/6/1085

Internet

https://www.mdpi.com/2076-393X/11/6/1085

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