Insight into Pathogenic Mechanism Underlying the Hereditary Cataract Caused by βB2-G149V Mutation

Insight into Pathogenic Mechanism Underlying the Hereditary Cataract Caused by βB2-G149V Mutation

Congenital cataracts account for approximately 5–20% of childhood blindness worldwide and 22–30% of childhood blindness in developing countries. Genetic disorders are the primary cause of congenital cataracts. In this work, we investigated the underlying molecular mechanism of G149V point missense m...

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Bibliographic Details
Main Authors: Jing Wu, Silong Chen, Jingjie Xu, Wanyue Xu, Sifan Zheng, Qing Tian, Chenqi Luo, Xiangjun Chen, Xingchao Shentu
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biomolecules
Subjects:
congenital cataract
βB2-crystallin
G149V mutation
spectral experiments
Online Access:https://www.mdpi.com/2218-273X/13/5/864

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https://www.mdpi.com/2218-273X/13/5/864

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