Exploration of Reduced Mitochondrial Content–Associated Gene Signature and Immunocyte Infiltration in Colon Adenocarcinoma by an Integrated Bioinformatic Analysis

Exploration of Reduced Mitochondrial Content–Associated Gene Signature and Immunocyte Infiltration in Colon Adenocarcinoma by an Integrated Bioinformatic Analysis

Purpose: Mitochondrial dysfunction refers to cancer immune evasion. A novel 7-gene prognostic signature related to the mitochondrial DNA copy number was utilized to evaluate the immunocyte infiltration in colon cancer according to the risk scores and to predict the survival for colon cancer.Experime...

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Bibliographic Details
Main Authors: Jinlin Kang, Na li, Fen Wang, Yan Wei, Yangyang Zeng, Qifan Luo, Xuehua Sun, Hui Xu, Jin Peng, Fuxiang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
mitochondiral DNA
Colon Cancer
Immunocyte infiltration
Bioinformatic analysis
Gene signature
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.832331/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.832331/full

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