Predicting enhancer-promoter interaction based on epigenomic signals

Predicting enhancer-promoter interaction based on epigenomic signals

Introduction: The physical interactions between enhancers and promoters are often involved in gene transcriptional regulation. High tissue-specific enhancer-promoter interactions (EPIs) are responsible for the differential expression of genes. Experimental methods are time-consuming and labor-intens...

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Bibliographic Details
Main Authors: Leqiong Zheng, Li Liu, Wen Zhu, Yijie Ding, Fangxiang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Genetics
Subjects:
enhancer-promoter interaction
machine learning
ChIA-PET
random forest
epigenomic signals
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1133775/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1133775/full

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