Acceleration of hepatic sterol synthesis after a single dose of the porphyrogenic chemical allylisopropylacetamide

Hepatic sterol synthesis is accelerated in animals after a single dose of allylisopropylacetamide, a chemical known to be porphyrogenic. Evidence is provided to show that enhanced sterol biosynthesis is due to an increased formation of mevalonic acid, indicating that the primary site of action of th...

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Bibliographic Details
Main Authors: Luigi Taddeini, Ivan Frantz, Jr., Ajit Sanghvi
Format: Article
Language:English
Published: Elsevier 1974-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752036836X