Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein

Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein

<p>Abstract</p> <p>Background</p> <p>There is increasing evidence for the role of High Risk (HR) Human PapillomaVirus (HPV) in the pathogenesis of Oral Squamous Cell Carcinoma (OSCC). The E6 and E7 oncogenes from HR HPVs are responsible for the deregulation of p53 and p...

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Bibliographic Details
Main Authors: Di Fede Olga, Cappello Francesco, Aragona Francesco, Amato Marco C, Arancio Walter, Rodolico Vito, Pannone Giuseppe, Campisi Giuseppina
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Infectious Agents and Cancer
Subjects:
Oral Squamous Cell Carcinoma
Hif-1α
HPV
HPV16
E7
Online Access:http://www.infectagentscancer.com/content/6/1/18

Internet

http://www.infectagentscancer.com/content/6/1/18

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