LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway

LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway

Diabetes could directly induce cardiac injury, leading to cardiomyopathy. However, treatment strategies for diabetic cardiomyopathy remain limited. ZNF593-AS knockout and cardiomyocyte-specific transgenic mice were constructed. In addition, high-fat diet (HFD)-induced diabetic mouse model and db/db...

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Bibliographic Details
Main Authors: Rong Xie, Jiahui Fan, Jianpei Wen, Kunying Jin, Jiabing Zhan, Shuai Yuan, Yuyan Tang, Xiang Nie, Zheng Wen, Huaping Li, Chen Chen, Dao Wen Wang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs
diabetic cardiomyopathy
ZNF593-AS
IRF3
lncRNA
diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123001117

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http://www.sciencedirect.com/science/article/pii/S2162253123001117

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